Lwala Community Alliance (Lwala) catalyzes the capabilities of communities to tackle the multidimensional drivers of poor health. It was founded by a group of community members in rural Kenya facing the dual crisis of maternal and child mortality, who organized to build their region’s first health clinic and then engaged the research prowess of Vanderbilt University to rigorously measure its interventions. Today, Lwala is much more than a hospital; it operates a community-led health model making dramatic improvements in maternal and child health, including a 97% skilled delivery rate, 300% increase in contraceptive uptake, 64% reduction in child mortality, 96% immunization rate, and virtual elimination of mother-to-child transmission of HIV.